杜杰，首都医科大学，北京市心肺血管疾病研究所，教授，博士生导师。1985年北京大学生物系学士，1989年中国农科院取得博士学位，当年赴美国留学。先后作为博士后、讲师、助理教授、副教授在美国Emory University School of Medicine, Baylor College of Medicine 从事心血管，高血压发生及其危害，肿瘤方面的研究。曾主持及参与多项美国NIH R01 心血管研究课题。2008年任教育部长江特聘教授。2008年获得国家自然科学基金杰出青年称号。 2010年教育部心血管重塑相关疾病重点实验室主任。2010年北京市第二批海外高层次人才。2011年教育部长江创新主动脉瘤研究团队主任。

目前任北京安贞医院院长助理，北京市心肺血管疾病研究所副所长，教授， 主持包括国家“973”课题，北京市心血管病理生理平台课题，国家自然科学基金重大、重点等基金。累计发表SCI论文已过百篇。

1. Du J*, Jia L, Li Y, Ma X. Add Another Killer for Interfered Vascular Function Natural Killer Cells–Produced Interferon-γ Is a Cue. Arterioscler Thromb Vasc Biol. 2013; 33select 6):1116-7.
2. Xue H, Xiao Z, Zhang J, Wen J, Wang Y, Chang Z, Zhao J, Gao X, Du J*, Chen YG*. Disruption of the Dapper3 gene aggravates ureteral obstruction-mediated renal fibrosis by amplifying Wnt/β-catenin signaling. J Biol Chem.  2013; 288select 21):15006-14.
3. Zhang Y, Wang Y, Liu Y, Wang N, Qi Y, Du J*. Krüppel-Like Factor 4 Transcriptionally Regulates TGF-β1 and Contributes to Cardiac Myofibroblast Differentiation. PloS One. 2013; 8select 4):e63424.
4. Zhang JM, Wang Y, Miao YJ, Zhang Y, Wu YN, Jia LX, Qi YF, Du J*. Knockout of CD8 Delays Reendothelialization and Accelerates Neointima Formation in Injured Arteries of Mouse via TNF-α Inhibiting the Endothelial Cells Migration. PloS One. 2013; 8select 5):e62001.
5. Lin J, LiH, Yang M, Ren J, Huang Z, Han F, Huang J, Ma J, Zhang D, Zhang Z, Wu J, Huang D, Qiao M, Jin G, Wu Q, Huang Y, Du J*, Han J*. A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Report. 2013; 3select 1):200-10.
6. Zeng Y, Wang HX, Guo SB, Yang H, Zeng XJ, Fang Q, Tang CS, Du J, Li HH. Transcriptional Effects of E3 Ligase Atrogin-1/MAFbx on Apoptosis, Hypertrophy and Inflammation in Neonatal Rat Cardiomyocyte. PLoS One. 2013; 8select 1):e53831.
7. Qin YW, Teng X, He JQ, Du J, Tang CS, Qi YF. Increased plasma levels of intermedin and brain natriuretic peptide associated with severity of coronary stenosis in acute coronary syndrome. Peptides. 2013; doi: 10.1016/j.peptides.2013.01.011.
8. Teng X, Bian Y, Cai Y, Duan X, Yuan F, Du J, Wu W, Wang X, Tang C, Qi Y. Downregulation of Endogenous Intermedin Augmented Myocardial Injury in Rats Ischemic/Reperfusion. Horm Metab Res. 2013; 45select 3):206-12.
9. Zhang C, Li Y, Wu Y, Wang L, Wang X, Du J*. Interleukin-6/STAT3 pathway is essential for macrophage infiltration and myoblast proliferation during muscle regeneration. J Biol Chem. 2012; 288select 3):1489-99.
10. Yang K, Zhang TP, Tian C, Jia LX, Du J, Li HH. Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein Inhibits Angiotensin II-Induced Cardiac Remodeling. Am J Hypertens. 2012; 25select 9):994-1001.
11. Liu O,  Jia L, Liu X,  Wang Y, Wang X, Qin Y,  Du J, Zhang H. Clopidogrel, a Platelet P2Y12 Receptor Inhibitor, Reduces Vascular Inflammation and Angiotensin II induced-Abdominal Aortic Aneurysm Progression. PLoS One. 2012; 7select 12):e51707.
12. Qin Y, Cao X, Guo J, Zhang Y, Pan L, Zhang H, Li H, Tang C, Du J, Shi GP. Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Cardiovasc Res. 2012; 96select 3):401-10.
13. Kikani CK, Verona EV,Ryu J,Shen Y, Ye Q, Zheng L, Qian Z, Sakaue H, Nakamura K, Du J, Ji Q, Ogawa w, Sun LZ, Dong LQ, Liu F. Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis. Sci. Signal. 2012; 5select 249):ra80.
14. Liang A, Wang Y, Woodard LE, Wilson MH, Sharma R, Awasthi YC, Du J, Mitch WE, Cheng J. Loss of Glutathione S-transferase A4 Accelerates Obstruction-induced Tubule Damage and Renal Fibrosis. J Pathol. 2012; 228:448-458.
15. Yang M, Zheng J, Miao Y, Wang Y, Cui W, Guo J, Qiu S, Han Y, Jia L, Li H, Cheng J, Du J*. Serum/glucocorticoid-regulated Kinase 1 Regulates Alternatively Activated Macrophage Polarization Contributing to Angiotensin II-induced Inflammation and Cardiac Fibrosis. Arterioscler Thromb Vascular Biol. 2012; 32select 7):1675-86.
16. Li Y, Zhang C, Wu Y, Han Y, Jia L, Cai L, Li H, Du J*. Deficiency of interleukin-12 promotes CD4 T cell-dependent macrophage differentiation and enhances angiotensin II-induced cardiac fibrosis Arterioscler Thromb Vascular Biol. 2012; 32select 7):1662-74.
17. Pan L, Li Y, Jia L, Qin Y, Qiu S, Qi G, Cheng J, Qi Y, Li H, Du J*. Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances angiotensin II–induced cardiac inflammation and fibrosis. PLoS One. 2012; 7select 4):e35315.
18. Ma F, Li Y, Jia L, Han Y, Li H, Qi Y, Du J*. Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF-?/Smad activation and cardiac fibrosis induced by angiotensin II. PLoS One. 2012; 7select 5):e35144.
19. Han Y, Li Y, Jia L, Cheng J, Qi Y, Du J*. Reciprocal Interaction between Macrophages and T cells Stimulates Interferon-? and MCP-1 Production in Angiotensin II-induced Cardiac Inflammation and Fibrosis. PLoS One. 2012; 7select 5):e35506.
20. Zhang L, Dong Y, Dong Y, Cheng J, Du J. The Role of Integrin-β3 in Macrophage Polarization and Regeneration of Injured Muscle. J Biol Chem. 2012; 287select 9):6177-86.
21. Zhou YB, Zhang J, Cai Y, Teng X, Duan XH, Song JQ, Du J, Tang CS, Qi YF. Insulin resistance induces medial artery calcification in fructose-fed rats. Exp Biol Med select Maywood). 2012; 237select 1):50-7.
22. Jia L, Li Y, Xiao C, Du J*. Angiotensin II induces inflammation leading to cardiac remodeling. Front Biosci. 2012; 17:221-31.
23.  Cheng J, Wang Y, Liang A, Jia L, Du J*. Silencing of FSP-1 in Bone Marrow Cells Suppresses Neointima Formation in Vein Graft. Circ Res.  2012; 110select 2):230-40.
24.  Zhao D, Qi Y, Zheng Z, Wang Y, Zhang XY, Li HJ, Liu HH, Zhang XT, Du J, Liu J. Dietary factors associated with hypertension. Nat Rev Cardiol. 2011; 8select 8):456-65.
25.  Teng X, Song J, Zhang G, Cai Y, Yuan F, Du J, Tang C, Qi Y. Inhibition of Endoplasmic Reticulum Stress by Intermededinselect 1-53) Protects Against Myocardioal Injury Through a PI3 kinase-Akt Signaling Pathway. J Mol Med 2011; 89select 12):1195-205.
26.  Chen G, Lin SC, Chen J, He L, Dong F, Xu J, Han S, Du J, Entman ML, Wang Y. CXCL16 recruits bone marrow-derived fibroblast precursors in renal fibrosis. J Am Soc Nephrol. 2011; 22select 10):1876-86.
27.  Wang Y, Zhao B, Zhang Y, Tang Z, Shen Q, Zhang Y, Zhang W, Du J, Chien S, Wang N. Krüppel-like Factor 4 is Induced by Rapamycin and Mediates the Anti-proliferative Effect of Rapamycin in Balloon-injured Rat Carotid Arteries. Br J Pharmacol. 2012; 165select 7):2378-88.
28.  Yang SW, Zhou YJ, Nie XM, Liu YY, Du J, Hu DY, Jia DA, Gao F, Hu B, Fang Z, Han HY, Liu XL, Yan ZX, Wang JL, Hua Q, Shi YJ, Li HW; BEAMIS Study Group. Effect of abnormal fasting plasma glucose level on all-cause mortality in older patients with acute myocardial infarction: results from the Beijing Elderly Acute Myocardial Infarction Study select BEAMIS). Mayo Clin Proc. 2011; 86select 2):94-104.
29. Yang H, Zeng XJ, Wang HX, Zhang LK, Dong XL, Guo S, Du J, Li HH, Tang CS. Angiotensin IV protects against angiotensin II-induced cardiac injury via AT4 receptor. Peptides. 2011; 32select 10):2108-15.
30.  Zhang Y, Kang YM, Tian C, Zeng Y, Jia LX, Ma X, Du J, Li HH. Overexpression of nrdp1 in the heart exacerbates Doxorubicin-induced cardiac dysfunction in mice. PLoS One. 2011; 6select 6):e21104.
31.  Li JJ, Zhang TP, Meng Y, Du J, Li HH. Stability of F-box Protein Atrogin-1 is Regulated by p38 Mitogen-activated Protein Kinase Pathway in Cardiac H9c2 Cells. Cell Physiol Biochem. 2011; 27select 5):463-70.
32.  Zheng Y, Wang M, Tian C, Ma X, Chen H, Du J, Li H. Osteopontin stimulates autophagy via integrin/CD44 and p38 MAPK signaling pathways in vascular smooth muscle cells. J Cell Physiol. 2012; 227select 1):127-35.
33.  Li W, Rong R, Zhao S, Zhu X, Zhang K, Xiong X, Yu X, Cui Q, Li S, Chen L, Cai J, Du J*. Proteomic analysis of metabolic, cytoskeletal, and stress response proteins in human heart failure. J Cell Mol Med. 2012; 16select 1):59-71.
34.  Qi G, Jia L, Li Y, Bian Y, Cheng J, Li H, Xiao C, Du J*  Angiotensin II Infusion-Induced Inflammation, Monocytic Fibroblast Precursor Infiltration and Cardiac Fibrosis is Pressure-Dependent. Cardiovasc Toxicol. 2011; 11select 2):157-67.
35.  Ren J, Yang M, Qi G, Zheng J, Jia L, Cheng J, Tian C, Li H, Lin X, Du J* . Proinflammatory Protein CARD9 is Essential for Infiltration of Monocytic Fibroblast Precursors and Cardiac Fibrosis Caused by Angiotensin II Infusion. Am J Hypertens. 2011; 24select 6):701-7.
36. Zhang Y, Zeng Y, Wang M, Tian C, Ma X, Chen H, Fang Q, Jia L, Du J*, Li H*. Cardiac-specific overxpression of E3 ligase Nrdp1 increases ischemia and reperfusion-induced cardiac injury Basic Res Cardiol. 2011; 106select 3):371-83.
37.   Li H, Du J, Fan Y, Zhang M, Liu D, Li L, Lockyer P, Kang E, Patterson C, Willis MS. The ubiquitin ligase Muscle Ring Finger-1 select MuRF1) protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun. Am J Pathology. 2011; 178select 3):1043-58.
38.   Zhang L, Rajan V, Liu E, Hu Z, Han HQ, Zhou X, Song Y, Min H, Wang X, Du J, Mitch W. Pharmacological Inhibition of Myostatin Suppresses Systemic Inflammation and Muscle Atrophy in Mice with Chronic Kidney Disease. FASEB J. 2011; 25select 5):1653-63.
39.   Cheng J, Wang Y, Ma Y, Yang M, Chan T, Zhang  L, Li H , and Du J*.  The mechanical stress-activated serum-, glucocorticoid-regulated kinase 1 contributes neointima formation in vein grafts. Circ Res. 2010; 107select 10):1265-74.
40. Cheng J, Truong LD, Wu X, Kuhl D, Lang F, Du J* . Serum- and glucocorticoid-regulated kinase 1 is upregulated following unilateral ureteral obstruction causing epithelial-mesenchymal transition. Kidney Int. 2010; 78select 7):668-78.
41. Liu S, Shen H, Xu M, Liu O, Zhao L, Liu S, Guo Z, Du J. FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model. Am J Physiol Endocrinol Metab. 2010; 299select 3):E351-63.
42.   Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, Trial J, Taffet GE, Entman ML. Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy.  J Mol Cell Cardiol. 2010;49select 3):499-507.
43.   Wu X, Cheng J, LiP Yang M, Qiu S, Liu P, Du J*.Mechano-Sensitive Transcriptional Factor Egr-1 Regulates Insulin-Like Growth Factor-1 Receptor Expression and Contributes to Neointima Formation in Vein Grafts.  Arterioscler Thromb Vasc Biol. 2010; 30select 3):471-6.
44.   HuZ, Wang H, Lee IH, Modi S, Wang X, Du J, Mitch WE. PTEN inhibition improves muscle regeneration in mice fed a high fat diet. Diabetes. 2010; 59select 6):1312-20.
45.   Wang XH, Zhang L, Mitch WE, LeDoux JM, Hu J, Du J*. Caspase-3 cleaves specific 19S proteasome regulatory subunits in skeletal muscle stimulating proteasome activity. J Biol Chem.  2010; 285select 28):21249-57.
46.   Hu J, Du J, Zhang LP, Pricce RS. Klein J Wang XH. Muscle Specific Expression of XIAP Blocks Proteolysis by Inhibition of Murf-1 in Chronicle Kidney Diseases Mice. J Am Soc Nephrol. 2010; 21select 7):1174-83.
47.   Zhang LP, Wang XH, Wang H, Du J, Mitch WE. Satellite Cell Dysfunction and Impaired IGF-1 Signaling cause CKD-Induced Muscle Atrophy. J Am Soc Nephrol.  2010; 21select 3):419-27.
48.   Qin YW, Ye P, He JQ, Sheng L, Wang LY, DU J. Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein E-deficient mice fed a "Western-style diet" by increasing PPAR α and γ expression and reducing TC, MMP-9, and Cat S levels. Acta Pharmacol Sin. 2010; 31select 10):1350-8.
49.   Liu O, Li JR, Gong M, Xu M, Du J*, Zhang HJ. Genetic analysis of six SNPs in candidate genes associated with high cross-race risk of development of thoracic aortic aneurysms and dissections in Chinese Han population. Acta Pharmacol Sin. 2010; 31select 10):1376-80.
50.   Wang XH, Du J, Klein J, Baiely J and Mitch WE. Exercise ameliorates chronic kidney disease-induced defects in muscle protein metabolism and progenitor cell function. Kidney Int.  2009; 76select 7):751-9.
51.   Zhang LP, Ran LM, Garcia GE, Wang XN, Han SH, Du J*, Mitch WE. Chemokine CXCL16 Regulates Neutrophil and Macrophage Infiltration into Injured Muscle Promoting Muscle Regeneration. Am J Pathol. 2009; 175select 6):2518-27.
52.   Hu Z, Wang H, Lee IN, Du J*, Mitch WE*. Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest. 2009; 119select 10):3059-69.
53.   Zhang LP, Du J*, Hu Z, Han G, Delafontaine P, Garcia G, Mitch WE. IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.  J Am Soc Nephrol. 2009; 20select 3):604-12.
54.   Wang X, Hu Z, Du J, Klein J. Cardiac muscle protein catabolism in diabetes mellitus: activation of the ubiquitin-proteasome system by insulin deficiency. Endocrinology.  2008; 149select 11):5384-90.
55.   Garcia GE, Troung LD, Li P, Zhang P, Du J, Chen JF, Feng L. Adenosine A2A receptor activation and macrophage-mediated experimental glomerulonephritis. FASEB J. 2008; 22select 2):445-54.
56.   Zhu Q, Youn H, Tang J, Tawfik O, Dennis K, Terranova PF, Du J, Raynal P, Thrasher JB, Li B. Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers. Oncogene. 2008; 27select 33):4569-79.
57.   Cheng JZ, Du J*. Mechanical stretch simulates proliferation of venous smooth muscle cells through activation of the insulin-like growth factor-1 receptor. Arterioscler Thromb Vasc Biol. 2007; 27select 8):1744-51.
58.   Cheng J, Zhang J, Merched A, Zhang L, Zhang P, Troung L Boriek AM, Du J*. Mechanical stretch inhibits oxidized low density lipoprotein-induced apoptosis in vascular smooth muscle cells by up-regulating integrin alphavbeta3 and stablization of PINCH-1. J Biol Chem. 2007; 282select 47):34268-75.
59.   Cheng JZ, Cui RW, Chen C, Du J*. Oxidized low-density lipoprotein stimulates p53-dependent activation of proapoptotic Bax leading to apoptosis of differentiated endothelial progenitor cells. Endocrinology.  2007; 148 select 5): 2085-94.
60.   Hu Z, Lee IH, Wang X, Sheng H, Zhang L, Du J and Mitch WE. PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes.  2007; 56select 10):2449-56.
61.   Zhou Q, Du J, Hu Z, Walsh K, Wang XH. Evidence for adipose-muscle cross talk: opposing regulation of muscle proteolysis by adiponectin and Fatty acids. Endocrinology. 2007; 148select 12):5696-705.
62.   Cheng JZ, Du J*. Mechanical Stretch Simulates Proliferation of Venous Smooth Muscle Cells through Activation of the Insulin-like Growth Factor-1 Receptor. Arterioscler Thromb Vasc Biol. 2007; 27select 8):1744-51.
63.   Cheng J, Zhang J, Merched A, Zhang L, Zhang P, Troung L Boriek AM, Du J*. Mechanical stretch suppresses Ox-LDL-induced apoptosis in vascular smooth muscle cells by upregulating integrin alphavbeta 3 and stabilization of PINCH-1. J Biol Chem. 2007; 282select 47):34268-75.
64.   Cheng JZ, Cui RW, Chen C, Du J*. Oxidized Low-density Lipoprotein Stimulates p53-dependent Activation of Pro-apoptotic Bax Leading to Apoptosis of Differentiated Endothelial Progenitor Cells. Endocrinology. 2007; 148 select 5): 2085-94.
65.   Hu Z, Lee IH, Wang X, Sheng H, Zhang L, Du J, Mitch WE. PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes.  2007; 56select 10):2449-56.
66.   Zhou Q, Du J, Hu Z, Walsh K, Wang XH. Evidence for Adipose-Muscle Crosstalk: Opposing Regulation of Muscle Proteolysis by Adiponectin and Fatty Acids. Endocrinology. 2007; 148select 12):5696-705.
67.   Wang X, Hu J, Du J, Klein J. X-cheromosome Linked inhibitor of apoptosis protein select XIAP) inhibits muscle proteolysis in insulin deficient mice. Gene Therapy. 2007; 14 select 9): 711-20.
68.   Ma Y, Zhang L, Peng T, Cheng J, Taneja S, Zhang J, Delafontaine P, Du J*. Angiotensin II Stimulates Transcription of Insulin-like Growth Factor 1 Receptor in Vascular Smooth Muscle Cells: Role of NF-?B. Endocrinology. 2006; 147select 3):1256-63.
69.   Workeneh BT, Rondon-Berrios H, Zhang L, Hu Z, Ayehu G, Ferrando A, Kopple JD, Wang H, Storer T, Fournier M, Lee SW, Du J, Mitch WE. Development of a Diagnostic Method for Detecting Increased Muscle Protein Degradation in Patients with Catabolic Conditions. J Am Soc Nephrol. 2006; 17select 11):3233-9.
70.   Wang X, Hu J, Hu Z, Du J, Mitch WE. Insulin Resistance Accelerates Muscle Protein Degradation: Activation of the Ubiquitin-Proteasome Pathway by Defects in Muscle Cell Signaling. Endocrinology. 2006; 147select 9):4160-8.
71.   Zhang L, Cheng J, Ma Y, Thomas W, Zhang J, Du J*. Dual Pathways for Nuclear Factor ?B Activation by Angiotensin II in Vascular Smooth Muscle: Phosphorylation of p65 by ?B Kinase and Ribosomal Kinase. Circ Res. 2005; 97select 10):975-82.
72.   Zhang L, Ma Y, Zhang J, Cheng J, Du J*. A New Cellular Signaling for Angiotensin II Activation of NF-?B:  an I?B-independent, RSK-mediated Phosphorylation of p65. Arterioscler Thromb Vasc Biol. 2005; 25select 6):1148-53.
73.   Zhang L, Cui R, Cheng X, Du J*. Anti-apoptotic Effect of Serum and Glucocorticoid-Inducible Protein Kinase is Mediated by Activating Nuclear Transcription Factor ?B. Cancer Res. 2005; 65select 2): 457-64.
74.   Song Y, Li Y, Du J, Mitch W., Rosenthal N and Delafontaine P. Muscle-Specific Expression of Insulin-like Growth Factor-1 Blocks Angiotensin II-induced Skeletal Muscle Wasting. J Clin Invest. 2005; 115select 2): 451-8.
75.   Higashi Y, Peng T, Du J, Sukhanov S, Li Y, Itabe H, Parthasarathy S, Delafontaine P. A Redox-sensitive Pathway Mediates Oxidized LDL-induced Downregulation of Insulin-like Growth Factor-1 Receptor. J Lipid Res. 2005; 46select 6):1266-77.
76.   Du J, Mitch WE. Identification of Pathways Controlling Muscle Protein Metabolism in Uremia and Other Catabolic Conditions. Curr Opin Nephrol Hypertens. 2005; 14select 4):378-82.
77.   Du J, Hu Z, Mitch WE. Molecular Mechanisms Activating Muscle Protein Degradation in Chronic Kidney Disease and Other Catabolic Conditions. Eur J of Clin Invest. 2005; 35select 3):157-63.
78.   Du J, Hu Z, Mitch WE. Cellular Signals Activating Muscle Proteolysis Chronic Kidney Disease: A Two Stage Process. Int Biochem Cell Biol. 2005; 37select 10):2147-55.
79.   Mitch W, Hu Z, Lee S, Du J. Strategies for Suppressing Muscle Atrophy in Chronic Kidney Disease: Mechanisms Activating Distinct Proteolytic Systems. J Renal Nutrition. 2005; 15select 1): 23-7.
80.   Lee SW, Dai G, Hu Z, Wang X, Du J, Mitch WE. Regulation of Muscle Protein Degradation: Coordinated Control of Apoptotic and Ubiquitin-proteasome Systems by Phosphatidylinositol 3 Kinase. J Am Soc Nephrol. 2004; 15 select 6): 1537-45.
81.   Mitch WE, Du J. Cellular Mechanisms Causing Loss of Muscle Mass in Kidney Disease. Semin Nephrol. 2004; 24select 5): 484-7.
82.   Du J, Wang X, Miereles C, Bailey J, Zheng B, Price S, Mitch W. Activation of Caspase-3 is an Initial Atep Triggering Accelerated Muscle Proteolysis in Catabolic Conditions. J Clin Invest. 2004; 13select 1):115-23.
83.   Li Y, HigashiY, Itabe H, Song YH, Du J, Delafontaine P. Insulin-like growth factor-1 receptor activation inhibits oxidized LDL-induced Cytochrome C Release and Apoptosis via the Phosphatidylinositol 3 Kinase/Akt Signaling Pathway. Arterioscler Thromb Vasc Biol. 2003; 23select 12):2178-84.
84.   Liao X, Thrasher J, Du J, Li B. GSK-3? Suppression Overcomes TRAIL Resistance in Prostate Cancer. Molecular Cancer Therapy 2003; 3:1215-21.
85.   Zhang J, Fu M, Myles D, Zhu X, Du J, Cao X, Chen Y. PDGF Induces Osteoprotegerin Expression in Vascular Smooth Muscle Cells by Multiple Signal Pathways. FASEB J. 2002; 521select 1-3):180-4.
86.   Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, Jo H. Shear Stress Stimulates Phosphorylation of eNOS at Ser1179 by Akt-independent Mechanisms - Role of Protein Kinase A. J Biol Chem. 2002; 277select 5): 3388-96.
87.   Franch H, Sooparb S, Du J .Phosphatidylinositol 3-Kinase Activity is Required for Epidermal Growth Factor to Suppress Proteolysis. J Am Soc Nephrol. 2002; 13select 4):903-9.
88.   Fu M, Zhu X, Xheng H, Du J, Chen E. Platelet-Derived Growth Factor Promotes the Expression of Peroxisome Proliferator-Activated Receptor ? in Vascular Smooth Muscle Cells by a Phosphatidylinositol 3-Kinase/Akt Signaling Pathway. Circ Res. 2001; 89select 11):1058-1064.
89.   Du J, Brink M, Peng T, Delafontaine P. Thrombin Regulates Insulin-like Growth Factor-1 Receptor Transcription in Vascular Smooth Muscle: Characterization of the Signaling Pathway. Circ Res. 2001; 88select 10):1044-52.
90.   Franch HA, Sooparb S, Du J, Brown NS. A Mechanism Regulating Proteolysis of Specific Proteins during Renal Tubular Cell Growth. J Biol Chem. 2001; 276select 22):19126-31.
91.   Price S, Du J, Bailey J, Mitch W.  Molecular Mechanisms Regulating Protein Turnover in Muscle.  Ame J of Kid Diseases. 2001; 37select 1):112-4.
92.   Du J, Mitch WE, Wang X, Price SR. Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-kappa B. J Biol Chem. 2000; 275select 26):19661-6.
93.   Du J, Peng T, Scheidegger KJ, Delafontaine, P. Angiotensin II Activation of Insulin-like Growth Factor 1 Receptor Transcription is mediated by a Tyrosine Kinase-Dependent Redox-sensitive Mechanism.  Arterioscler Thromb Vasc Biol. 1999; 19select 9):2119-26.
94.   Scheidegger K, Du J, Delafontaine P. Distinct and Common Pathways in the Regulation of Insulin-like Growth Factor-1 Receptor Gene Expression by Angiotensin II and Basic Fibroblast Growth Factor. J Biol Chem.1999; 274select 6):3522-30.
95.   Mitch WE, Du J, Bailey JL, Price SR. Mechanisms Causing Muscle Proteolysis in Uremia: The Influence of Insulin and Cytokines. Miner Electrolyte Metab. 1999; 25select 4-6):216-19.
96.   Delafontaine P, Brink M, Du J.  Angiotensin II Modulation of Insulin-like Growth Factor 1 Expression in the Cardiovascular System. Trends Cardiova Med. 1996; 6select 6):187-93.
97.   Du J, Meng XP, Delafontaine P. Transcriptional Regulation of the Insulin-like Growth Factor-1 Receptor Gene: Evidence for Protein Kinase C-dependent and Independent Pathways. Endocrinology 1996; 137select 4):1378-84.
98.   Du J, Sperling LS, Marrero MB, Phillips L, Delafontaine P. G-protein and Tyrosine Kinase Receptor Cross-talk in Rat Aortic Smooth Muscle Cells: Thrombin- and Angiotensin II-induced Tyrosine Phosphorylation of Insulin Receptor Substrate-1 and Insulin-like Growth Factor 1 Receptor.  Biochem Biophys Res Commun. 1996; 218select 3):934-9.
99.   Delafontaine P, Meng XP, Ku L, Du J.  Regulation of Vascular Smooth Muscle Cell Insulin-like Growth Factor 1 Receptors by Phosphorothioate Oligonucleotides.  Effects on Cell Growth and Evidence That Sense Targeting at the ATG site Increases Receptor Expression. J Biol Chem. 1995; 270select 24):14383-8.
100. Du J, Delafontaine P. Inhibition of Vascular Smooth Muscle Cell Growth through Antisense Transcription of a Rat Insulin-like Growth Factor 1 Receptor cDNA. Cir Res. 1995; 76select 6):963-72.